RETAVASE® (reteplase) is a recombinant plasminogen activator which catalyzes the cleavage of endogenous plasminogen to generate plasmin. Plasmin degrades the fibrin matrix of the thrombus, exerting its thrombolytic action.
Proven efficacy in acute STEMI1‑3
More patients achieved TIMI 2 or 3 flow at 90 minutes with RETAVASE® (reteplase) in the RAPID studies compared with alteplase1-3
Two clinical studies compared patency rates 90 minutes after treatment with RETAVASE or two different regimens of alteplase in patients with acute STEMI. Partial or complete flow (TIMI grades 2 or 3) and complete flow (TIMI grade 3) were reported.